SKIP003114 : N1-iPSC_HGPS
| Cell Line Name | N1-iPSC_HGPS |
|---|---|
| Original Database URL | |
| Database | |
| Species | Human |
| Type | iPS Cell |
| Original Tissue | Skin |
| Disease Status | Gene carrier |
| Description | |
| Cell Morphology | human ES-like |
| Grade | Research Grade |
Method for Establishment
| Vector | Retrovirus | |
|---|---|---|
| Transgene | OCT4, SOX2, KLF4, and C-MYC | |
| Feeder Cell | Yes | murine feeder |
| Medium | 0.5 mM valproic acid in human ESC medium | |
Pluripotency Tests
| Pluripotent Markers | Yes | Assay | qRT-PCR, Immunohistology |
|---|---|---|---|
| in vitro Differentiation | Yes | Assay | Immunostaining |
| in vivo Differentiation | Yes | Assay | teratoma formation |
Chromosomal QC
| Karyotype | Yes | Assay | G-band |
|---|
No data available
| Disease Name | Hutchinson-Gillford progeria syndrome (HGPS) | ICD10 | E34.8 |
|---|---|---|---|
| OMIM ID | 176670 | ||
| Age | 41 | ||
| Sex | Female | ||
| Race | Caucasian | ||
| Genetic Analysis | Yes | ||
Journal
Contact Information
| # | Name | Organization | Contact Email |
|---|---|---|---|
| 1 | Jinqiu Zhang | A-STAR Institute of Medical Biology, Singapore |
Information Provider
| # | Name | Organization | Contact Email |
|---|---|---|---|
| 1 | Alan Colman | A-STAR Institute of Medical Biology, Singapore |
Provider/Distributor
| # | Availability | Organization | URL | |
|---|---|---|---|---|
| 1 | Information Only |